Martine J. Smit,Sergio A. Lira,Rob Leurs's Chemokine Receptors as Drug Targets, Volume 46 (Methods and PDF

By Martine J. Smit,Sergio A. Lira,Rob Leurs

ISBN-10: 3527321187

ISBN-13: 9783527321186

Chemokines are hormone-like signaling molecules secreted by means of cells to sign an infection and advisor the immune reaction. Following a decade of uncomplicated chemokine examine, the pharmaceutical has now started to take advantage of this important signaling pathway for the advance of cutting edge medicinal drugs opposed to AIDS, melanoma, neural and autoimmune ailments. this is the 1st reference targeting those novel drug improvement opportunities.
starting with a normal advent on chemokine functionality and chemokine receptor biology, the second one half covers the recognized implications of those signaling molecules in human illnesses, resembling melanoma, neural issues, and viral an infection, together with AIDS. The 3rd half systematically surveys present drug improvement efforts at concentrating on person chemokine receptors, in addition to different chemokine interplay companions, together with updated experiences from the pharmaceutical industry.

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Chemokine Receptors as Drug Targets, Volume 46 (Methods and Principles in Medicinal Chemistry) by Martine J. Smit,Sergio A. Lira,Rob Leurs

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